Archive for March, 2008

French judges investigate vaccine manufacturer for manslaughter

Wednesday, March 19th, 2008

In what was called a “thunderclap in the vaccine industry,” French authorities have opened a formal investigation concerning a hepatitis B vaccination campaign by GlaxoSmithKline and Sanofi Pasteur in the 1990s. It is alleged that the companies failed to fully disclose neurologic side effects. Another investigation opened by Judge Marie-Odile Bertella-Geffroy concerns the death (“manslaughter”) of a 28-year-old woman from multiple sclerosis, allegedly connected to the vaccine (Le Figaro 1/31/08).

From 1994 to 1998, almost two-thirds of the French population and almost all newborn babies were vaccinated against hepatitis B, but the campaign was temporarily suspended because of concerns about side effects.

Some 30 plaintiffs, including the families of five patients who died after the vaccination, have launched civil actions (Reuters 1/1/08).

A British case-controlled analysis showed an odds ratio of 3.1 (95% CI 1.5-6.3) for first symptoms of multiple sclerosis in recipients of recombinant hepatitis B vaccine compared to controls. Two previous French studies had shown a RR of about 1.5. Other studies showed a nonsignificant increase or null findings, especially when date of diagnosis rather than date of first symptoms was used (Neurology 2004;63:838-842).

According to attorney Clifford Miller, “British doctors administering hepatitis B vaccine to infants could face criminal prosecution if fully informed consent is not obtained. Civil prosecution for damages is possible over 21 years later if the injured survive as adults” (UK Press Association Newswire/Romeike, September 2005).

The hepatitis B vaccine has been considered “one of the safest vaccines ever produced” (Neurology, op. cit.). On the other hand, French medical expert Marc Girard has said that “for a preventive measure, hepatitis B is remarkable for the frequency, variety and severity of complications from its use” (Romeike, op.cit.)

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Registry for egg donors proposed after young woman dies of colon cancer

Saturday, March 15th, 2008

After her daughter died at age 31 of colon carcinoma, Dr. Jennifer Schneider of Tucson wondered whether three cycles of egg donation might have been related. She is asking Congress to create a registry of egg donors. Research on the long-term effects of egg donation are not now possible because many donations are anonymous, and there is little, if any, follow-up care.Most prospective donors “don’t know the difference between being told ‘We don’t know of any significant long-term risks’ and ‘There are no significant long-term risks,’” Dr. Schneider said.

High doses of hormones are taken prior to the donation. Jessica Grace Wing had started donating eggs at age 25. She was diagnosed with advanced colon carcinoma at age 29. Her mother recently read a 1998 article in the British journal Human Reproduction, which reported a case of a woman who had donated her eggs, then died of colon cancer (Tucson Citizen 3/5/08).

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Vaccine compensation fund to pay award to autistic girl; broad implications feared

Monday, March 10th, 2008

Although an attorney representing the federal government said that it “has not conceded that vaccines cause autism,” Associated Press headlines read that “officials concede vaccines’ link to illness like autism” (AP 3/6/08). Petitioner Hannah Joling, now 9 years old, received 5 vaccines at once in 2000. According to a document that AP obtained from the U.S. Department of Health and Human Services, this aggravated an underlying mitochondrial disorder, causing metabolic dysfunction manifesting as worsened brain function with features of autistic spectrum disorder.

The document drew no conclusions as to the role of thimerosal. The government has previously denied any link at all between vaccine components and autism.

A Portuguese study suggested that 7% of autistic children might have a mitochondrial disorder, compared to 0.02% in the whole population.

Stories are conflicting about the time of onset of Hannah’s symptoms. Some state that she had suggestive symptoms at age 3 months; others that she was developing normally until the vaccines were given at 19 months. Her father Jon Poling, M.D., Ph.D., a neurologist, and mother, who is a lawyer and nurse, contend that the vaccines were also responsible for their daughter’s mitochondrial disorder (Kent Heckenlively, Age of Autism 3/5/08).

The family has filed a request with the court to unseal the documents on the case. A spokesman for the U.S. Department of Justice, which represents the government in all cases, refused to grant interviews or to explain to the Atlanta Journal-Constitution why it isn’t releasing the records (Alison Young, Atlanta Journal-Constitution 3/6/08).

The 5,000 families seeking compensation for autism or other developmental disorders they blame on vaccines are encouraged by the decision, the first of its type. However, each case needs to be proved on its own merits, and the decision is so narrowly worded that it may not be a helpful precedent.

Whatever the cause, the number of children receiving Supplemental Social Security Income (SSI) for disability has more than tripled in 20 years. In 1960, only 1.8% of U.S. children or adolescents were said by their parents to have a limitation of activity due to a health condition of more than 3 months’ duration; this rate had increased to more than 7% by 2004. Conditions include obesity, asthma (which has doubled since the 1980s), and attention-deficit/hyperactivity disorder (ADHD, affecting some 6% of schoolchildren).

Potential causative factors, according to JAMA, include maternal smoking (although its prevalence has decreased), poverty (which is stable), and “fast foods.” The only suggested role for the large increase in the number of vaccines is that less or less normal stimulation of the immune system, owing to less exposure to viral infections in early childhood, could cause greater susceptibility to allergens (JM Perrin, et al., JAMA 6/27/07).

There is also a significant increase in both type 1 and type 2 diabetes mellitus in children, at least partly attributed to obesity (RB Lipton, JAMA 6/26/07). Some wonder whether this too could have a link to vaccines. Hemophilus immunization has been associated with autoantibodies to islet cells. A Danish study recently showed an attributable risk of 2.3/100 (2.3%) of type 1 diabetes from hemophilus immunization in siblings of insulin-dependent diabetic children (JB Classen, Open Ped Med J 2/25/08).

Establishing the role of vaccines in any chronic, disabling condition could open floodgates of demand for compensation. And this single case of compensation for autism is making public health officials and pediatricians worry that parents will skip vaccinations.

A CDC panel voted unanimously to recommend influenza vaccine annually for all school-age children (WorldNetDaily 2/28/08). New Jersey officials have told parents that their babies can’t attend day care without their flu shot. Most influenza vaccine contains thimerosal.

Two other vaccine-court cases testing the alleged connection between thimerosal and autism go to trial in May.

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Economic shocks straight ahead?

Thursday, March 6th, 2008

As former Comptroller General David Walker told 60 Minutes, the unfunded liabilities of entitlement programs, especially Medicare, are so huge that even shutting down the Pentagon would not help significantly. He states that leaving this huge debt to the next generation is morally wrong. He does not, however, address the question of who will continue to lend us the money that subsequent generations will have to repay. Apparently, it has been assumed that the funds would be forthcoming.

If the U.S. loses its triple-A credit rating—which is the anchor of the world financial system—severe global consequences would follow. This could occur within a decade (Francesco Guerrera et al., Financial Times 1/11/08).

The subprime mortgage crisis has exposed much deeper concerns. As more borrowers defaulted, banks and other institutional investors began discovering that they owned huge quantities of a new security, collateralized debt obligations or CDOs, which many financial writers don’t even understand. CDOs quickly became the most important influence on home values in America, writes Stephen Mihm (“The Black Box Economy,” Boston Globe 1/27/08).

Mortgage-driven securities are “but the tip of a much larger iceberg,” Mihm observes. Quoting Bill Gross, manager of the world’s largest bond mutual fund, he writes: “Our modern shadow banking system craftily dodges the reserve requirements of traditional institutions and promotes a chain letter, pyramid scheme of leverage, based in many cases on no reserve cushion whatsoever.”

We could see “failing banks, busted brokerages, toppled corporate giants, bankrupt cities, states in default, foreign creditors cashing out of U.S. securities,” warns Gerald Celente, director of the Trends Research Institute in Rhinebeck, N.Y. He predicts that the dollar will bottom out at 10 cents on the euro, perhaps by 2010, and notes that even some Third-World vendors are refusing payment in greenbacks. Formerly invited onto television and cable networks, Celente is now shunned, and USA Today did not cover the Trends Report for the first time in decades, writes Christopher Ketchum (“Trends for Downsizing the U.S.: the Bright Side of the Panic of ’08,” Pacific Free Press 1/31/08).

Arthur Robinson notes an immediate problem: 30% of U.S. energy is now produced abroad, costing $400 billion per year. “Either the government gets off the backs of our energy industries—especially our hydrocarbon and nuclear energy industries, or else the citizens of the United States will become the bankrupt inhabitants of a low-technology country” (Access to Energy, November 2007). Oil and gas that we now import will be purchased by “countries who are able to pay with goods and services and real money, rather than unpayable debt and fiat money.”

Of all the presidential candidates, only Ron Paul has acknowledged the seriousness of the impending economic crisis. The stimulus package will not do the job, he says. “Unfortunately, too many in Washington still believe that we can spend our way into prosperity. This will not work and never has.” Business and jobs go overseas when “taxes bleed away profits and burdensome regulation hamstrings operations,” Paul writes (Ron Paul’s Texas Straight Talk 1/27/08).

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