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	<title>Comments on: Poling case intensifies debate; vaccine-autism link worth investigating, says former NIH director</title>
	<atom:link href="http://www.aapsonline.org/newsoftheday/0027/feed" rel="self" type="application/rss+xml" />
	<link>http://www.aapsonline.org/newsoftheday/0027</link>
	<description>from the Association of American Physicians and Surgeons</description>
	<pubDate>Fri, 21 Nov 2008 03:47:01 +0000</pubDate>
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		<title>By: Clifford G. Miller</title>
		<link>http://www.aapsonline.org/newsoftheday/0027#comment-1328</link>
		<dc:creator>Clifford G. Miller</dc:creator>
		<pubDate>Fri, 30 May 2008 04:22:02 +0000</pubDate>
		<guid isPermaLink="false">http://www.aapsonline.org/newsoftheday/?p=27#comment-1328</guid>
		<description>Regarding this item from the
AAPS news:- 

&lt;blockquote&gt;"Paul Offit,
M.D., co-inventor of the rotavirus
vaccine RotaTeq, writes
that the Vaccine Injury Compensation Program (VICP) “seems to have
turned its back on science.” Instead of a preponderance of evidence, it
now simply requires that an expert propose a plausible mechanism for
vaccine injury."
  &lt;/blockquote&gt;
Clearly, Offit knows nothing
of the standard approach to the
assessment of adverse drug reactions when this is a subject he should
know fully if he has any concern for vaccine safety and therefore for
the child health safety of US kids.&#160; 

When deciding if a drug caused an adverse drug reaction, biological
plausibility is all that is required.&#160; See:-

&lt;blockquote&gt;&lt;a href="http://www.medsafe.govt.nz/Profs/adverse/causality.asp" rel="nofollow"&gt;Adverse
Reaction Reporting and IMMP - Causality Assessment of Suspected Adverse
Medicine Reactions&lt;/a&gt;&lt;/blockquote&gt;
Whereas of course,
dechallenge, rechallenge and dose-response are
far more important, and of course the Japanese data is conclusive:-

&lt;blockquote&gt;&lt;a href="http://homepage.ntlworld.com/clifford.g.miller/hondarutter.html" rel="nofollow"&gt;Strong
Evidence Mercury &#38; Vaccines Cause Autism&lt;/a&gt;&lt;/blockquote&gt;
So this also means Offit is
ignorant of a key aspect of
pharmacology (adverse drug reaction reporting) which every medical
general practitioner should know.&#160; 

Additionally, Offit is just as ignorant about evidence.&#160;
Biological
plausibility will obviously meet also the "preponderance of evidence"
requirement.&#160; It assists in the decision of whether it is "more
plausible than not" which I think everyone recognises is a
"preponderance of evidence" except of course for Dr Offit.&#160; 

Aren't his colleagues at the Childrens' Hospital of Philadelphia
embarrassed yet by this man?

</description>
		<content:encoded><![CDATA[<p>Regarding this item from the<br />
AAPS news:- </p>
<blockquote><p>&#8220;Paul Offit,<br />
M.D., co-inventor of the rotavirus<br />
vaccine RotaTeq, writes<br />
that the Vaccine Injury Compensation Program (VICP) “seems to have<br />
turned its back on science.” Instead of a preponderance of evidence, it<br />
now simply requires that an expert propose a plausible mechanism for<br />
vaccine injury.&#8221;
  </p></blockquote>
<p>Clearly, Offit knows nothing<br />
of the standard approach to the<br />
assessment of adverse drug reactions when this is a subject he should<br />
know fully if he has any concern for vaccine safety and therefore for<br />
the child health safety of US kids.&nbsp; </p>
<p>When deciding if a drug caused an adverse drug reaction, biological<br />
plausibility is all that is required.&nbsp; See:-</p>
<blockquote><p><a href="http://www.medsafe.govt.nz/Profs/adverse/causality.asp" rel="nofollow">Adverse<br />
Reaction Reporting and IMMP - Causality Assessment of Suspected Adverse<br />
Medicine Reactions</a></p></blockquote>
<p>Whereas of course,<br />
dechallenge, rechallenge and dose-response are<br />
far more important, and of course the Japanese data is conclusive:-</p>
<blockquote><p><a href="http://homepage.ntlworld.com/clifford.g.miller/hondarutter.html" rel="nofollow">Strong<br />
Evidence Mercury &amp; Vaccines Cause Autism</a></p></blockquote>
<p>So this also means Offit is<br />
ignorant of a key aspect of<br />
pharmacology (adverse drug reaction reporting) which every medical<br />
general practitioner should know.&nbsp; </p>
<p>Additionally, Offit is just as ignorant about evidence.&nbsp;<br />
Biological<br />
plausibility will obviously meet also the &#8220;preponderance of evidence&#8221;<br />
requirement.&nbsp; It assists in the decision of whether it is &#8220;more<br />
plausible than not&#8221; which I think everyone recognises is a<br />
&#8220;preponderance of evidence&#8221; except of course for Dr Offit.&nbsp; </p>
<p>Aren&#8217;t his colleagues at the Childrens&#8217; Hospital of Philadelphia<br />
embarrassed yet by this man?</p>
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